Next-Generation Protein Sequencing™ to Detect Disease-Relevant Proteoforms

Summary

Dr. Gloria Sheynkman’s presentation at the Festival of Genomics highlights the importance of detecting protein isoforms for understanding human traits and diseases. She introduces a novel long-read proteogenomics workflow to enhance protein isoform detection. Additionally, she describes how the Platinum® Next-Generation Protein Sequencer™ offers single-molecule protein sequencing technology with high sensitivity and resolution.

Platinum provides robust peptide sequencing capabilities, complementing traditional mass spectrometry (MS) methods, and underscores the need for integrating orthogonal technologies to advance proteomics research and detect disease-relevant proteoforms.